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1

Phosphoramidate ProTides of the Anticancer Agent FUDR Successfully Deliver the Preformed Bioactive Monophosphate in Cells and Confer Advantage over the Parent Nucleoside

McGuigan, Christopher, Murziani, Paola, Slusarczyk, Magdalena, Gonczy, Blanka, Vande Voorde, Johan, Liekens, Sandra, Balzarini, Jan

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.05 MB

english, 2011

2

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer

Casciano, Jessica C., Perry, Caroline, Cohen-Nowak, Adam J., Miller, Katelyn D., Vande Voorde, Johan, Zhang, Qifeng, Chalmers, Susan, Sandison, Mairi E., Liu, Qin, Hedley, Ann, McBryan, Tony, Tang, Hs

Journal:

British Journal of Cancer

Year:

2020

Language:

english

File:

PDF, 2.66 MB

english, 2020

3

ChemInform Abstract: Synthesis and Biological Evaluation of Unsaturated Keto and Exomethylene D-Arabinopyranonucleoside Analogues: Novel 5-Fluorouracil Analogues that Target Thymidylate Synthase.

Niki Tziomaki, Stella Manta, Evangelia Tsoukala, Johan Vande Voorde, Sandra Liekens, Dimitri Komiotis, Jan Balzarini

Journal:

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

4

Synthesis and biological evaluation of unsaturated keto and exomethylene d-arabinopyranonucleoside analogs: Novel 5-fluorouracil analogs that target thymidylate synthase

Niki Tzioumaki, Stella Manta, Evangelia Tsoukala, Vande Voorde Johan, Sandra Liekens, Dimitri Komiotis, Jan Balzarini

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 437 KB

english, 2011

5

In vitro and in vivo studies on the importance of the soluble gyanylyl cyclase alpha 1 subunit in penile erection

Kelly Decaluwé, Sofie Nimmegeers, Robrecht Thoonen, Peter Brouckaert, Vande Johan Voorde

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 72 KB

english, 2009

6

Evidence for the Presence ofLegionellaBacteriophages in Environmental Water Samples

Elke Lammertyn, Johan Vande Voorde, Eef Meyen, Liesbeth Maes, Jan Mast, Jozef Anné

Journal:

Microbial Ecology

Year:

2008

Language:

english

File:

PDF, 338 KB

english, 2008

7

The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes

Johan Vande Voorde, Sandra Liekens, Christopher McGuigan, Paola G.S. Murziani, Magdalena Slusarczyk, Jan Balzarini

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

8

Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-d-ribose-1-phosphate derivative

Johan Vande Voorde, Maurizio Quintiliani, Christopher McGuigan, Sandra Liekens, Jan Balzarini

Journal:

Biochemical Pharmacology

Year:

2012

Language:

english

File:

PDF, 358 KB

english, 2012

9

Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis : implications for the clinical efficacy of nucleoside analogues

Vande Voorde, Johan, Gago, Federico, Vrancken, Kristof, Liekens, Sandra, Balzarini, Jan

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.63 MB

english, 2012

10

Evidence for the Presence of Legionella Bacteriophages in Environmental Water Samples

Elke Lammertyn, Johan Vande Voorde, Eef Meyen, Liesbeth Maes, Jan Mast and Jozef Anné

Journal:

Microbial Ecology

Year:

2008

Language:

english

File:

PDF, 1.31 MB

english, 2008

11

The Nurture of Tumors Can Drive Their Metabolic Phenotype

Schug, Zachary T., Vande Voorde, Johan, Gottlieb, Eyal

Journal:

Cell Metabolism

Year:

2016

Language:

english

File:

PDF, 440 KB

english, 2016

12

Mycoplasma hyorhinis -encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs

Vande Voorde, Johan, Vervaeke, Peter, Liekens, Sandra, Balzarini, Jan

Journal:

Year:

2015

Language:

english

File:

PDF, 730 KB

english, 2015

13

The metabolic fate of acetate in cancer

Schug, Zachary T., Voorde, Johan Vande, Gottlieb, Eyal

Journal:

Nature Reviews Cancer

Year:

2016

Language:

english

File:

PDF, 741 KB

english, 2016

14

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

Bulusu, Vinay, Tumanov, Sergey, Michalopoulou, Evdokia, van den Broek, Niels J., MacKay, Gillian, Nixon, Colin, Dhayade, Sandeep, Schug, Zachary T., Vande Voorde, Johan, Blyth, Karen, Gottlieb, Eyal,

Journal:

Year:

2017

Language:

english

File:

PDF, 3.80 MB

english, 2017

15

Increased formate overflow is a hallmark of oxidative cancer

Meiser, Johannes, Schuster, Anne, Pietzke, Matthias, Voorde, Johan Vande, Athineos, Dimitris, Oizel, Kristell, Burgos-Barragan, Guillermo, Wit, Niek, Dhayade, Sandeep, Morton, Jennifer P., Dornier, Em

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.18 MB

english, 2018

16

Improving the metabolic fidelity of cancer models with a physiological cell culture medium

Vande Voorde, Johan, Ackermann, Tobias, Pfetzer, Nadja, Sumpton, David, Mackay, Gillian, Kalna, Gabriela, Nixon, Colin, Blyth, Karen, Gottlieb, Eyal, Tardito, Saverio

Journal:

Science Advances

Year:

2019

Language:

english

File:

PDF, 2.79 MB

english, 2019

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